Optimization of microwave-assisted extraction of polysaccharides in the flower of Platycodon grandiflorum by response surface methodology

Abstract

Platycodon grandiflorum polysaccharides (PGPs) are naturally occurring compounds derived from the flowers of platycodon grandiflorum. the microwave assisted extraction (MAE) of PGPs was studied. A three-level and three-factor Box–Behnken design was used to optimize MAE conditions, and the effects of operating conditions including microwave power (180-540 W), extraction time (20-60 s) and liquid to solid ratio (20-30 v/w) on the extraction yield of PGPs were studied through response surface methodology (RSM). The results showed that the highest yield of PGPs reached 8.35 g/(100 g) at 360 W microwave power, 40 s extraction time and 25.2 v/w liquid to solid ratio. The extraction yield of PGPs was significantly affected by liquid to solid ratio (P